Tag: 南京夜网MC

Go back to the enewsletter

first_imgGo back to the e-newsletter Go back to the e-newsletterZegrahm Expeditions has announced three brand-new expeditions in 2017. Each year the 25-year-old expedition company crafts a unique selection of itineraries on all seven continents, using the personal knowledge of its experienced field leaders and feedback from its traveller community. Comprising signature expeditions—such as Antarctica, South Georgia & the Falkland Islands and Australia’s Kimberley—as well as new itineraries like the three featured below, the company’s annual line-up is thoughtfully curated for guests to pursue their passion for exploration, adventure and learning.Philippines, Taiwan & Japan11 – 29 March 2017Far from the usual tourist track, other tour operators rarely, if ever, visit many of the islands on this itinerary. The perfect blend of nature and culture, travellers will discover remote island communities, explore unique habitats on nature hikes, search for a variety of marine life during snorkelling and diving excursions, and observe both ancient and modern architectural treasures.Cultural Mongolia with the Naadam Festival2 – 18 July 2017Showcasing Mongolia’s unique culture and breathtaking landscapes on a 17-day journey that includes the opportunity to experience Mongolia’s traditional mid-summer festival, Naadam, at both the national and local levels. Meaning “the three games of men”, Naadam showcases Mongolian wrestling, horse racing and archery—traditional sports that are as exhilarating to watch as they are essential to Mongolia’s identity as a country.Along the Irrawaddy & Chindwin Rivers15 September – 3 October 2017Exposing travellers to river scenes of a bygone era—dense jungles, steep-sided gorges, emerald rice paddies and tiny traditional villages—aboard the elegant 46-guest Anawrahta, built in 2014 to resemble a British colonial paddle steamer. A particular highlight of this expedition is a visit to the Mahar Minkyaung Monastery, an extraordinary blend of European and Burmese architecture that houses the 1000-year-old Shwe Sagar Buddha.“These three adventures really show what Zegrahm does best: adding new destinations—or unique combinations of new destinations—to complement our tried-and-true itineraries to offer something for first-time adventure travellers and seasoned past guests alike,” says Zegrahm President, Van Perry. “We couldn’t be more excited to explore these new corners of Asia in 2017.”Virtuoso members can take advantage of the conference exclusive announced during Virtuoso Travel Week: Offer your clients a $1000 per person air credit on small-ship cruises and $500 per person air credit on overland adventures — and you’ll receive a $500 booking bonus.last_img read more

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Study uncovers unconventional killer T cells capable of combating viral infections

first_imgMay 2 2018Research led by the University of Birmingham has identified a novel unconventional type of immune cell capable of fighting viral infections.The study, published today in Nature Communications and carried out in collaboration with the Academic Medical Center, Netherlands, and Skolkovo Institute of Science and Technology, Russia, focussed on T cells that control our immune system.Specifically the research has defined a subset of ‘unconventional V-delta-2 lymphocytes’, which are a type of Gamma Delta T cell – an ancient class of immune cell that has been relatively poorly understood.The new findings establish that this subtype is not only present at birth, but persists in adults at low levels, and can increase in numbers massively during virus infections.Related StoriesComprehensive cell atlas of the human liverAlternate cell growth pathway could open door to new treatments for metastatic cancersNANOLIVE‘s novel CX-A defines a new standard for live cell imaging in 96 well plates for continuous organelle monitoring in cell populationsThe researchers examined how this subtype of T cell responded to a virus infection called cytomegalovirus. They found that when these T cells detected signs of the virus infection they both increased in numbers and became ‘licensed to kill’.Lead Author Dr Martin Davey, of the University of Birmingham’s Institute of Immunology and Immunotherapy, said:”These cells can clearly adapt to some key challenges that life throws at them.”Upon viral infection, they change from harmless precursors into what appear to be ruthless killers.”They can then access tissues, where we believe they detect and destroy virally infected target cells.”The results build on previous work from the same research group, published last month in Trends in Immunology, which also suggests that many gamma delta T cells that control our immune system can adapt in the face of infectious challenges.The team is now trying to better understand the scenarios when these unconventional killer T cells are most important and how to harness them to advance treatments to fight viral infections.Dr Davey added: “We think these cells contribute to defense against viral infection in the liver, a site which is exposed to many potentially dangerous infectious diseases.”They may also be particularly important when other aspects of our immune system are not working at full strength, such as in newborn babies, but also in transplant patients who are taking immunosuppressive drugs to prevent organ rejection.”In these scenarios, boosting the activity of these cells could prove beneficial to patients, and we are now starting to explore how to do that.” Source:https://www.birmingham.ac.uk/news/latest/2018/05/immune-cells-viral-infection-killer.aspxlast_img read more

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